L-(+)-Ergothioneine /CAS:497-30-3

 specification

 Usage

Ergothioneine has extensive applications and promising market prospects in organ transplantation, cell preservation, pharmaceuticals, food and beverages, functional foods, animal feed, cosmetics and biotechnology.

As a non-toxic natural antioxidant with strong cytoprotective properties, it is resistant to oxidation in aqueous solutions. For this reason, its concentration in certain tissues can reach the millimolar level, and it activates the body's natural cellular antioxidant defense system.

Distinct from many other antioxidants, ergothioneine is capable of chelating heavy metal ions and protecting red blood cells in the body from damage caused by free radicals.

Ergothioneine is a potent scavenger of hypochlorous acid (HOCl). While numerous compounds can react with hypochlorous acid, few do so as rapidly as ergothioneine.

Alpha-1-antiproteinase inhibitor (API), such as elastase, is highly susceptible to hypochlorous acid. At physiological concentrations, ergothioneine can effectively protect API against hypochlorous acid-induced inactivation. Since neutrophils are the major source of hypochlorous acid in the human body, ergothioneine helps shield red blood cells from damage caused by neutrophils at normal functional sites or inflamed lesions.

Ergothioneine (abbreviated as ET or EGT) is a rare natural amino acid derivative. In 1909, Charles Tanret isolated a unique crystalline sulfur-containing compound while studying ergot fungi that infest rye grains. This water-soluble thiol was later named ergothioneine after the ergot fungus.

EGT is widely found in microbial cells, plants and animals, with relatively high levels in foods such as mushrooms, black beans, red beans and oats. As an endogenous substance in the human body, EGT accumulates at high concentrations in various cells and tissues, especially in red blood cells, bone marrow, liver, kidneys, semen, as well as the lens and cornea of the eyes.

Certain microorganisms including mycobacteria can synthesize EGT, but the human body cannot produce it independently and must obtain and accumulate it through dietary intake.

Chemically, ergothioneine is a derivative of sulfur-containing amino acids. Its stable sulfur atom accounts for its distinctive antioxidant capacity. The sulfur atom traps and neutralizes free radicals, thus alleviating oxidative stress and damage to cells. In addition, ergothioneine is lipophilic, enabling it to penetrate cell membranes and exert effects inside cells, which further enhances its antioxidant performance.

Ergothioneine is scarce in nature. Besides ergot fungi, trace amounts can also be detected in some other fungi, bacteria and plants. Nevertheless, human beings mainly acquire it from daily diets, including ingredients such as golden oyster mushrooms, ganoderma lucidum and cordyceps.

Packaging and Shipping

25KG/Drum or as customer requirements.
Belongs to common goods and can deliver by ocean and air

Keep and storage

Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.