L-(+)-Ergothioneine /CAS:497-30-3
Inkcazo emfutshane:
Igama lemveliso: L-(+)-Ergothioneine
Uhlobo:ZA-N
I-CAS:497-30-3
MF:C9H15N3O2S
I-MW: 229.3
ULWAKHIWO:
iqondo lokunyibilika: 275-277°C (ngoDisemba)
iinkcukacha
| Jonga into | Iinkcukacha |
| Iipropati | Umgubo omhlophe ukuya komhlophe ocwebezelayo |
| Ubunyulu | ≥99.0% |
| umxholo | ≥99.0% |
| Ukufuma | ≤1% |
| Intsimbi enzima | ＜10ppm |
| Iintsholongwane ze-aerobic zizonke | ＜750cfu/g |
| Inani lemvubelo kunye nokungunda | ＜25cfu/g |
| I-Escherichia coli | Okungalunganga |
| I-Salmonella | Okungalunganga |
| I-Staphylococcus | Okungalunganga |
Ukusetyenziswa
I-Ergothioneine inezicelo ezininzi kunye namathuba athembisayo emarikeni ekufakelweni kwamalungu omzimba, ukugcinwa kweeseli, amayeza, ukutya neziselo, ukutya okusebenzayo, ukutya kwezilwanyana, izinto zokuthambisa kunye ne-biotechnology.
Njenge-antioxidant yendalo engenabungozi eneempawu ezinamandla zokukhusela i-cytoprotective, ayixhathisi kwi-oxidation kwizisombululo zamanzi. Ngenxa yesi sizathu, uxinano lwayo kwizicubu ezithile lunokufikelela kwinqanaba le-millimolar, kwaye luvuselela inkqubo yokuzikhusela ye-antioxidant yeseli yomzimba.
Yahlukile kwezinye ii-antioxidants ezininzi, i-ergothioneine inako ukukhupha ii-ion zesinyithi esinzima kunye nokukhusela iiseli ezibomvu zegazi emzimbeni kumonakalo obangelwa zii-free radicals.
I-Ergothioneine sisithako esinamandla sokukhupha i-hypochlorous acid (HOCl). Nangona iikhompawundi ezininzi zinokusabela kwi-hypochlorous acid, zimbalwa ezenza oko ngokukhawuleza njenge-ergothioneine.
I-Alpha-1-antiproteinase inhibitor (API), efana ne-elastase, ichaphazeleka kakhulu yi-hypochlorous acid. Kwizinga le-physiological, i-ergothioneine inokukhusela ngokufanelekileyo i-API kwi-hypochlorous acid-induced inactivation. Ekubeni ii-neutrophils zingumthombo ophambili we-hypochlorous acid emzimbeni womntu, i-ergothioneine inceda ukukhusela iiseli ezibomvu zegazi ekonakaleni okubangelwa zii-neutrophils kwiindawo eziqhelekileyo zokusebenza okanye kwizilonda ezivuvukileyo.
I-Ergothioneine (efinyezwa njenge-ET okanye i-EGT) sisixhobo esingaqhelekanga sendalo esiphuma kwi-amino acid. Ngo-1909, uCharles Tanret wahlula i-compound ekhethekileyo ene-crystalline sulfur ngelixa wayefunda nge-ergot fungi ehlasela iinkozo ze-rye. Le thiol enyibilikayo emanzini kamva yabizwa ngokuba yi-ergothioneine emva kwe-ergot fungus.
I-EGT ifumaneka kakhulu kwiiseli zeentsholongwane, izityalo kunye nezilwanyana, kwaye amanqanaba aphezulu ekutyeni okufana namakhowa, iimbotyi ezimnyama, iimbotyi ezibomvu kunye nee-oats. Njengento ephilayo emzimbeni womntu, i-EGT iqokelelana ngamanani aphezulu kwiiseli ezahlukeneyo kunye nezicubu, ngakumbi kwiiseli ezibomvu zegazi, umongo wethambo, isibindi, izintso, isidoda, kunye nelensi kunye ne-cornea yamehlo.
Iintsholongwane ezithile kuquka i-mycobacteria zinokwenza i-EGT, kodwa umzimba womntu awukwazi ukuyivelisa ngokwawo kwaye kufuneka uyifumane kwaye uyiqokelele ngokutya.
Ngokwekhemikhali, i-ergothioneine yi-derivative ye-amino acids equlethe i-sulfur. I-atom yayo ye-sulfur ezinzileyo ibangela amandla ayo ahlukileyo e-antioxidant. I-atom ye-sulfur ibamba kwaye ithintele ii-free radicals, ngaloo ndlela inciphisa uxinzelelo lwe-oxidative kunye nomonakalo kwiiseli. Ukongeza, i-ergothioneine i-lipophilic, ivumela ukuba ingene kwiimembrane zeseli kwaye isebenzise iziphumo ngaphakathi kwiiseli, nto leyo ephucula ngakumbi ukusebenza kwayo kwe-antioxidant.
I-Ergothioneine ayifumaneki lula. Ngaphandle kwe-ergot fungi, inani elincinci leentsholongwane lingafunyanwa nakwezinye iifungi, iibhaktheriya kunye nezityalo. Nangona kunjalo, abantu bayifumana kakhulu kwizidlo zemihla ngemihla, kuquka izithako ezifana nee-golden oyster mushrooms, i-ganoderma lucidum kunye ne-cordyceps.
Ukupakishwa kunye nokuthunyelwa
25KG/Idrama okanye ngokweemfuno zomthengi.
Yeyokwempahla eqhelekileyo kwaye inokuhanjiswa ngolwandle nangomoya
Gcina kwaye ugcine
Ixesha lokuphelelwa: Iinyanga ezingama-24 ukususela kumhla wokwenziwa kwayo kwiphakheji yokuqala engavulwanga igcinwe kwindawo epholileyo neyomileyo kude nelanga elithe ngqo, amanzi.
Indawo yokugcina umoya, Ukomisa kubushushu obuphantsi, Yahlulwe kwii-oxidants, ii-asidi.
