page_banner

products

Glutathione CAS:70-18-8

Short Description:

Product name: Glutathione

CAS: 70-18-8

Density: 1.4482

Molecular formulaC10H17N3O6S

Molecular weight307.32


Product Detail

Product Tags

 specification

Item

Specifications

Appearance

White crystalline powder

Assay

≥98.0%

Optical rotation

-15.5—-17.5

Loss on drying

≤0.5

Ash content

≤0.1

Heavy metals

≤20

Arsenic

≤2

 Usage

The molecular weight of glutathione is 307.33, with a melting point of 189-193℃ (decomposition). The crystal is colorless, transparent, slender and columnar, and the isoelectric point is 5.93. It is soluble in water, dilute alcohol, liquid ammonia and methylformamide, but insoluble in alcohol, ether and acetone. Only GSH has physiological activity in organisms, while GSSG needs to be reduced before it can exert its important physiological functions. GSH is not easy to preserve under high water activity. Only by controlling the water activity below 0.3 can it be stably preserved for a long time. Studies have shown that in a vitamin C aqueous solution containing GSH (pH3.3), due to the strong reducing effect of vitamin C, GSH in the solution will not be oxidized to GSSG, but its decomposition rate accelerates. The GSSG existing in the aqueous solution of vitamin C will not be transformed into GSH and has good preservation stability. Moreover, the GSSG ingested orally can be reduced to GSH in the upper part of the small intestine. It is absorbed on the surface of small intestinal epithelial cells through the action of γ-GTP(which decomposes GSH into glutamic acid and Cys-Gly) and dipeptidase, and can also exert its important physiological functions.

Reduced glutathione is a small molecule peptide that is abundantly present in living organisms, especially in liver cells. It has the functions of protecting the liver cell membrane, promoting the activity of liver enzymes, and combining with many toxic chemicals to play a detoxification role. It has a very good therapeutic effect on liver injuries caused by various reasons such as drug poisoning and alcohol poisoning, as well as diseases like liver cirrhosis.

It has functions such as antioxidation, free radical scavenging, detoxification, enhancing immunity, delaying aging, anti-cancer and resisting the harm of radiation.
Glutathione can be used as a biochemical reagent and antidote, mainly for the treatment of poisoning from heavy metals, acrylonitrile, fluorides, carbon monoxide and organic solvents, etc.
Endogenous antioxidants that play a significant role in the reduction of reactive oxygen species formed during cellular metabolism and sudden respiration. Glutathione -S-transferase catalyzes the formation of glutathione sulfide with heteroorganisms, leukotrienes and other molecules with electrophilic centers. Glutathione also forms disulfide bonds with cysteine residues in proteins. Through these mechanisms, it can have the strange effect of reducing the efficacy of anti-cancer agents.

Packaging and Shipping

25KG/Drum or as customer requirements.
Belongs to common goods and can deliver by ocean and air

Keep and storage

Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.


  • Previous:
  • Next:

  • Write your message here and send it to us