Aside ya Ursodeoxycholic / UDCA / CAS: 128-13-2
Ibisobanuro bigufi:
Izina ry'igicuruzwa: aside ya Ursodeoxycholic
CAS: 128-13-2
Ubwoko: ZA-Y
MF:C24H40O4
MW: 392.57
IMITERERE:
Ibisobanuro:
Aside ya Ursodeoxycholic (UDCA) ni aside ya bile ya kabiri ifasha mu kugenzura cholesterol. Isesengura rya UDCA rishingiye kuri spectrometry rikorwa buri gihe mu isuzuma ry’indwara nko gupima amakosa y’abana bavutse mu ikorwa ry’aside ya bile, gutandukanya ubwoko bw’indwara yo mu nda y’umwijima, no gukurikirana uburyo umurwayi yitabira ubuvuzi bwa UDCA. Iyi solution yemewe yo guteka ibinure ikwiriye nk'igikoresho cyo gutangira mu gutegura amahame ngenderwaho, ibipimo, n'uburyo bwo kugenzura bukoreshwa mu gupima aside ya bile ya LC-MS/MS na GC/MS.
Ibisobanuro:
| Ikintu | Ibisobanuro |
| Aho gushonga | 203-204 °C (izuba) |
| Aho kubira | 437.26°C (ikigereranyo cy'ubushyuhe) |
| Ubucucike | 0.9985 (ikigereranyo cy'ibiciro) |
| Fp | 9℃ |
| Igipimo cy'ikirahure | 60.5 ° (C=2, EtOH) |
| Ubushyuhe bwo kubika. | 2-8°C |
| Gushonga | ethanoli: 50 mg/mL, idafite ubuziranenge |
| Ifishi | Ifu ikomeye. |
| Ibara | Umweru - hafi umweru. |
Imikoreshereze
Aside ya Ursodeoxycholic ni umunyu w’ibinure usanzwe mu bantu. Yinjizwa vuba mu mara mato hanyuma igasohoka hamwe n’ibinure. Aside ya Ursodeoxycholic ni umuti wa choise uvura indwara ya cirrhose y’ibinure na cholanite y’ibinure. Igipimo cya buri munsi kingana na 10-15 mg/kg. Nta ngaruka mbi igira nubwo yavurwa mu gihe cy’imyaka 20.
Imisemburo y'utubuye. Ikoreshwa cyane cyane mu kuvura utubuye tw'utu ...
Aside ya Ursodeoxycholic ishobora kandi kongera ubushobozi bwa α-interferon mu kuvura indwara ya hepatite C idakira. Ishobora kandi gukoreshwa mu kuvura impiswi, impatwe idakunze kugaragara, ingaruka z'ubwivumbure, kuribwa umutwe, isereri, ububabare bwo mu gifu, pancreatitis na bradycardia Abarwayi bafite ikibazo cy'imyakura idakora neza cyangwa umwijima udakora neza cyane n'abagore batwite bagomba kwirinda kuyikoresha.
Aside ya Ursodeoxycholic (UDCA) ni umuti urinda uturemangingo ukoreshwa cyane mu kugabanya indwara z'umwijima n'iz'inda. Aside ya Ursodeoxycholic ishobora gukoreshwa mu kwiga ibikorwa byayo byihariye kuva ku kugabanya kwinjiza cholesterol, gushonga kwa cholesterol mu gallstone kugeza ku kugabanya ubudahangarwa bw'umubiri. Ikoreshwa kandi nk'umuti urwanya kolelithiolisi. Epimer hamwe na Chenodiol ugereranije n'itsinda rya hydroxyl kuri C7.
Gupakira no Kohereza
25KG/Ingoma.
Ni iy'ibicuruzwa rusange kandi ishobora gutangwa binyuze mu nyanja no mu kirere
Bika kandi ubibike
Igihe cyo kubika: Amezi 24 uhereye igihe byakorewe mu ipaki y’umwimerere idafunguye, bibitswe ahantu hakonje kandi humutse, kure y’izuba ryinshi, amazi.
Ububiko bufite umwuka uhagije, Butuma ibintu bishya bishyuha, butandukanyijwe n'ibikomoka kuri okiside, aside.
