Ursodeoxycholic acid/UDCA/CAS: 128-13-2
Kev Piav Qhia Luv:
Lub Npe Khoom: Ursodeoxycholic acid
CAS: 128-13-2
Hom: ZA-Y
MF: C24H40O4
MW:392.57
QAUV:
Kev piav qhia:
Ursodeoxycholic acid (UDCA) yog ib qho kua qaub thib ob uas pab tswj cov roj cholesterol. Kev tshuaj xyuas UDCA raws li pawg spectrometry feem ntau ua rau hauv kev kuaj mob hauv tsev kho mob xws li kev kuaj menyuam mos ntawm cov teeb meem hauv plab ntawm cov kua qaub, kev sib txawv ntawm cov hom kab mob hauv tsev neeg, thiab kev saib xyuas kev kho mob ntawm cov neeg mob teb rau UDCA kev kho mob. Daim Ntawv Pov Thawj Spiking Solution no yog qhov tsim nyog ua cov khoom siv pib hauv kev npaj cov qauv linearity, calibrators, thiab kev tswj hwm rau kev siv hauv LC-MS/MS thiab GC/MS cov txheej txheem kuaj kua qaub.
Kev Qhia Tshwj Xeeb:
| Khoom | Cov Lus Qhia Tshwj Xeeb |
| Qhov kub yaj | 203-204 °C (lit.) |
| Kub taw tes | 437.26°C (kwv yees li qub) |
| Qhov Ceev | 0.9985 (kwv yees li qub) |
| Fp | 9 ℃ |
| Cov ntsuas kev cuam tshuam | 60.5 ° (C=2, EtOH) |
| Cia txias. | 2-8°C |
| Kev yaj tau | ethanol: 50 mg/mL, ntshiab |
| Daim Ntawv | Khoom khov. Hmoov. |
| Xim | Dawb - yuav luag dawb. |
Kev Siv
Ursodeoxycholic acid yog ib hom ntsev uas muaj nyob hauv tib neeg lub cev. Nws nqus tau sai sai hauv txoj hnyuv me thiab tso tawm nrog cov kua tsib. Ursodeoxycholic acid yog cov tshuaj siv los kho mob cirrhosis ntawm txoj hnyuv thiab mob sclerosis ntawm txoj hnyuv. Cov tshuaj noj txhua hnub yog 10-15 mg/kg. Nws tsis muaj kev phiv txawm tias tom qab kho mob txog li 20 xyoo.
Kev yaj cov pob zeb hauv lub zais zis. Feem ntau yog siv rau kev kho cov pob zeb hauv lub zais zis uas tsis tuaj yeem phais tau, nws yuav muaj qhov nrawm kho tau tshwj xeeb tshaj yog thaum lub zais zis zoo li qub, cov pob zeb muaj 15 hli lossis qis dua, nkag mus rau hauv X-ray, cov pob zeb tsis muaj calcified thiab cov pob zeb cholesterol ntab siab.
Ursodeoxycholic acid kuj tseem tuaj yeem txhim kho qhov ua tau zoo ntawm α-interferon rau kev kho mob kab mob siab C ntev. Nws kuj tseem siv tau los kho mob raws plab, cem quav tsawg, ua xua, khaus, mob taub hau, kiv taub hau, mob plab, pancreatitis thiab bradycardia Cov neeg mob uas muaj kev thaiv biliary lossis mob siab ua haujlwm hnyav thiab cov poj niam cev xeeb tub yuav tsum tsis txhob siv.
Ursodeoxycholic acid (UDCA) yog ib yam khoom siv tiv thaiv cell uas siv ntau yam los txo cov kab mob hepatic thiab biliary. Ursodeoxycholic acid siv tau los kawm txog nws cov dej num tshwj xeeb uas suav nrog kev txo qis ntawm kev nqus roj cholesterol, kev yaj ntawm cov pob zeb hauv lub zais zis mus rau kev tiv thaiv kab mob. Nws kuj tseem siv tau ua ib qho anticholelithogenic. Epimer nrog Chenodiol piv rau pawg hydroxyl ntawm C7.
Ntim thiab Xa Khoom
25KG / Nruas.
Yog cov khoom siv dav dav thiab tuaj yeem xa los ntawm dej hiav txwv thiab huab cua
Khaws cia thiab khaws cia
Lub neej txee: 24 lub hlis txij li hnub tsim khoom hauv cov ntim khoom tsis tau qhib khaws cia rau hauv qhov chaw txias thiab qhuav kom tsis txhob raug tshav ntuj ncaj qha, dej.
Lub tsev rau khoom muaj cua nkag, ziab kom qhuav kub tsawg, Sib cais ntawm cov tshuaj oxidants, cov kua qaub.
