Ursodeoxycholic acid/UDCA/CAS: 128-13-2
Takaitaccen Bayani:
Sunan Samfura: Ursodeoxycholic acid
CAS: 128-13-2
Nau'i: ZA-Y
MF:C24H40O4
MW:392.57
TSARI:
Bayani:
Ursodeoxycholic acid (UDCA) wani sinadari ne na bile acid wanda ke taimakawa wajen daidaita cholesterol. Ana yin nazarin UDCA bisa ga yawan gwaje-gwaje akai-akai a cikin gwaje-gwajen asibiti kamar gwajin kurakuran da aka haifa a cikin jarirai na haɗakar bile acid, bambance-bambance tsakanin nau'ikan cholestasis na cikin hanta, da kuma sa ido kan martanin marasa lafiya ga maganin UDCA. Wannan Maganin Spiking da aka Tabbatar ya dace a matsayin kayan farawa don shirya mizanan layi, masu daidaitawa, da sarrafawa don amfani a cikin hanyoyin gwajin bile acid na LC-MS/MS da GC/MS.
Bayani dalla-dalla:
| Abu | Ƙayyadewa |
| Wurin narkewa | 203-204 °C (haske) |
| Wurin tafasa | 437.26°C (kimanin ƙiyasin) |
| Yawan yawa | 0.9985 (kimanin ƙiyasin) |
| Fp | 9℃ |
| Ma'aunin haske | 60.5 ° (C=2, EtOH) |
| Zafin ajiya. | 2-8°C |
| Narkewa | ethanol: 50 mg/mL, bayyananne |
| Fom ɗin | Foda mai ƙarfi. |
| Launi | Fari - kusan fari. |
Amfani
Ursodeoxycholic acid gishiri ne na bile a cikin ɗan adam. Yana shiga cikin ƙananan hanji cikin sauri kuma yana fita tare da bile. Ursodeoxycholic acid magani ne na choise don maganin cutar cirrhosis ta biliary da kuma cutar sclerosis ta farko. Yawan da ake sha a kowace rana ya kai 10-15 mg/kg. Ba shi da wata illa ko da bayan tsawon lokacin magani har zuwa shekaru 20.
Narkewar duwatsun gallstone. Ana amfani da shi galibi don maganin duwatsun gallstone marasa aiki, zai sami saurin warkewa musamman idan gallstone ya zama al'ada, duwatsu suna da diamita na 15mm ko ƙasa da haka, suna shiga cikin X-ray, ba su da sinadarin calcium kuma suna da yawan cholesterol.
Ursodeoxycholic acid kuma yana iya inganta ingancin α-interferon wajen magance cutar hepatitis C mai tsanani. Haka kuma ana iya amfani da shi don magance gudawa, maƙarƙashiya mai wuya, rashin lafiyan halayen, kaikayi, ciwon kai, jiri, ciwon ciki, pancreatitis da bradycardia. Marasa lafiya da ke fama da toshewar biliary ko matsalar hanta mai tsanani da mata masu juna biyu ya kamata su guji amfani da shi.
Ursodeoxycholic acid (UDCA) wani maganin kariya ne na ƙwayoyin halitta da ake amfani da shi sosai don rage cututtukan hanta da biliary. Ana iya amfani da Ursodeoxycholic acid don nazarin takamaiman ayyukansa waɗanda suka haɗa da rage shan cholesterol, narkewar cholesterol gallstone zuwa rage martanin garkuwar jiki. Hakanan ana amfani da shi azaman maganin hana kumburi. Epimer tare da Chenodiol dangane da rukunin hydroxyl a C7.
Marufi da Jigilar Kaya
25KG/Drum.
Ya kasance na kayan yau da kullun kuma yana iya isar da kaya ta teku da iska
Ajiyewa da adanawa
Rayuwar shiryayye: Watanni 24 daga ranar ƙera shi a cikin marufi na asali wanda ba a buɗe ba, an adana shi a wuri mai sanyi da bushewa, ba tare da hasken rana kai tsaye ba, ko ruwa.
Ma'ajiyar iska, Busar da ƙananan zafin jiki, An raba shi da sinadarai masu guba, acid.
