Nikotinamide/CAS:98-92-0
Ibisobanuro bigufi:
Izina ry'igicuruzwa: Nikotinamide
Ubwoko: ZA-N
CAS: 98-92-0
MF:C6H6N2O
MW: 122.12
IMITERERE:
Ubucucike: 1.40
aho gushonga: 182 °C
Niacinamide ni ifu y'umweru isa n'urushinge rwa kristu cyangwa ifu ya kristu, nta mpumuro cyangwa impumuro gato, ifite uburyohe busharira gato. Ubucucike bwayo ni 1.4, kandi aho ishongesha ni 129-131℃. 1g y'iki gicuruzwa ishobora gushonga muri 1mL y'amazi, 1.5mL ya ethanol, cyangwa 10mL ya glycerol, ariko ntabwo ishongeshwa muri ether. pH y'umuti w'amazi wa 10% ni 6.5-7.5. Ifite hygroscopicity nke. Irahamye, irwanya aside, alkali, n'ubushyuhe bwinshi. Irahamye ku rumuri n'ubushyuhe mu kirere cyumye, ariko iyo ishyushye mu bisubizo bya alkali cyangwa aside, ikora aside nikotine. LD50 yo mu kanwa mu mbeba ni 2.5-3.5g / kg, kandi agaciro ka ADI ntikagaragazwa neza (ECC, 1990).
ibipimo
| IBICURUZWA | IBISOBANURO | IKIZAMINI IBISUBIZO |
| Isura | Ifu y'umweru ya kristali | Amategeko n'amabwiriza |
| Gushonga | Ishonga mu mazi no muri ethanol idafite amazi, ishonga gato muri methylene chloride | Amategeko n'amabwiriza |
|
Indangamuntu | A: Kwinjizwa kwa infrared | Amategeko n'amabwiriza |
| B: Kwinjizwa kwa Ultraviolet. Igipimo cya A245/A262 ni 0.63-0.67 | 0.66 | |
| C. Chromatrzphy y'urwego ruciriritse | Amategeko n'amabwiriza | |
| Isuzuma (%) | 99.0~101.0 | 100.1 |
| Intera yo gushonga (□) | 128~131 | 128.7-130.2 |
| Ishusho y'umuti | Nta mabara menshi cyane kurusha igisubizo cy'icyitegererezo BY7 | Amategeko n'amabwiriza |
| PH | 6.0~7.5 | 6.86 |
| Ibiyobyabwenge bya Relzted | Isuzuma nk'uko bigaragara kuri EP10.0 | Amategeko n'amabwiriza |
| Ibintu bishobora gukaraba byoroshye | Igisubizo cy'icyitegererezo nta bara rirenze iry'amazi ahuye na yo | Amategeko n'amabwiriza |
| Igihombo ku kumisha (%) | 20.5 | 0.03 |
| Ivu rigizwe na sulfure (%) | 20.1 | 0.0 |
| Ibisigazwa biri ku ishyushya (%) | ≤0.1 | 0.0 |
| Ibikoresho by'icyuma biremereye (mglkg) | ≤20 | -20 |
| UMWANZURO | Yujuje ibisabwa (Kuzuza ibisabwa) hamwe na USP2022 na EP10.0stkandird) | |
Imikoreshereze
- Gukamura, kugenzura amavuta, no kugabanya ubushyuhe bw'umukara: Niacinamide ishobora kugabanya neza igihombo cy'amazi ya transepidermal. Nubwo ingaruka zayo iyo zikoreshejwe zonyine zitaba nziza nk'iza aside hyaluronic na glycerin, ingaruka iyo zikoreshejwe hamwe ni 1+1>2; niacinamide ishobora gutuza imiterere y'uturemangingo tw'ibinure "dukora cyane", bityo ikagabanya ubushyuhe bw'umukara n'ibiheri.
- Ubushobozi bwiza bwo kurwanya iminkanyari: Ubushobozi bwa niacinamide bwo kurwanya iminkanyari buri mu bushobozi bwayo bwo gukora ATP, gutanga imbaraga kuri keratinocytes, kongera collagen synthesis, kandi ifite ubushobozi bwiza bwo guhuza ibikorwa, ishobora gukoreshwa hamwe n'ibindi bintu birwanya iminkanyari.
- Ingaruka nziza ku ruhu mu kurinda izuba: Kwangirika kw'imirasire ya ultraviolet ku mubiri w'umuntu si uguhindura ibara ry'umubiri gusa, ahubwo ni no kugabanya ubudahangarwa bw'umubiri (Chemicalbook) ndetse na kanseri y'uruhu. Ubushakashatsi bwinshi bwakorewe mu gihugu no mu mahanga bwagaragaje ko niacinamide ishobora kugabanya kugaragara k'ubudahangarwa bw'umubiri mu gihe cy'imirasire ya ultraviolet.
- Ubwiyoroshye: Ugereranyije n'ibintu nka vitamine C na resorcinol derivatives, niacinamide ni yoroshye cyane kandi ishobora gukoreshwa n'abantu bafite uruhu rwinshi. Ariko, hakwiye kwitabwaho kwihanganira uruhu. Urugero, The Ordinary Whitening Essence ifite 10% bya niacinamide iracyafite uburibwe runaka. Kubwibyo, ni byiza gukora ikizamini cyo kwihanganira uruhu mbere yo kuyikoresha. Ikoreshe gusa nyuma yo kwemeza ko ishobora kwihanganira, kandi icyarimwe, witondere kuyikoresha hamwe n'ibintu birimo aside nka aside salicylic na aside y'imbuto kugira ngo wirinde ko uruhu rugira uburibwe bwinshi.
Ikomoka kuri amide ikomoka kuri vitamine B3 na PARP inhibitor
Imiti ya Vitamine igira uruhare mu mikorere y’umubiri kandi ikoreshwa mu gukumira no kuvura pellagra n’izindi ndwara zo kubura niacin.
Niacinamide ifite ubushobozi bwo gushonga neza kurusha niacin, ariko yoroshye gukora ibintu bitandukanye birimo vitamine C n'udutsi duto. Igipimo ni 30-80mg/kg. Iyo ikoreshejwe mu bikoresho byo kwita ku ruhu, ishobora kurinda uruhu rudakomeye, kubungabunga ubuzima bw'uturemangingo tw'uruhu, no gutuma uruhu rwera. Iyo ikoreshejwe mu kwita ku misatsi, ishobora gutuma amaraso atembera neza mu mutwe, igakomeza kugira ubuzima bwiza bw'imitsi, ikanafasha gukura k'umusatsi, kandi ikarinda gutakaza umusatsi.
Gupakira no Kohereza
25KG/Ingoma cyangwa nk'uko umukiriya abikeneye.
Ni iy'ibicuruzwa rusange kandi ishobora gutangwa binyuze mu nyanja no mu kirere
Bika kandi ubibike
Igihe cyo kubika: Amezi 24 uhereye igihe byakorewe mu ipaki y’umwimerere idafunguye, bibitswe ahantu hakonje kandi humutse, kure y’izuba ryinshi, amazi.
Ububiko bufite umwuka uhagije, Butuma ibintu bishya bishyuha, butandukanyijwe n'ibikomoka kuri okiside, aside.
