Nicotinamide/CAS:98-92-0
Nkọwa Dị Mkpirikpi:
Aha ngwaahịa: Nicotinamide
Ụdị:ZA-N
CAS:98-92-0
MF:C6H6N2O
MW: 122.12
ỤDỊ:
Njupụta: 1.40
ebe agbaze: 182°C
Niacinamide bụ ntụ ntụ kristal ọcha ma ọ bụ kristal, nke na-enweghị isi ma ọ bụ na-esi ísì ntakịrị, nwere ụtọ ilu ntakịrị. Njupụta ya dị 1.4, ebe agbaze ya bụ 129-131℃. 1g nke ngwaahịa a nwere ike ịgbaze na 1mL mmiri, 1.5mL nke ethanol, ma ọ bụ 10mL nke glycerol, mana ọ bụghị na ether. pH nke mmiri 10% bụ 6.5-7.5. O nwere hygroscopicity na-adịghị ike. Ọ kwụsiri ike, na-eguzogide acid, alkalis, na okpomọkụ dị elu. Ọ kwụsiri ike na ìhè na okpomọkụ na ikuku kpọrọ nkụ, mana mgbe a na-ekpo ọkụ na ngwọta alkaline ma ọ bụ acidic, ọ na-emepụta nicotinic acid. LD50 ọnụ na oke bụ 2.5-3.5g/kg, a kọwaghịkwa uru ADI kpọmkwem (ECC, 1990).
nkọwapụta
| IHE | Nkọwapụta | ULE Nsonaazụ |
| Ọdịdị | Ntụ ntụ ọcha | Na-agbaso |
| Mmiri na-agbaze | A naghị agbaze n'ime mmiri na ethanol na-anaghị agbaze, ọ na-agbaze ntakịrị na methylene chloride | Na-agbaso |
|
Nchọpụta | A: Ntinye infrared | Na-agbaso |
| B:Mbubata Ultraviolet. Oke A245/A262 bụ 0.63-0.67 | 0.66 | |
| C. Kromatogrzphy dị gịrịgịrị | Na-agbaso | |
| Nnyocha (%) | 99.0~101.0 | 100.1 |
| Oke agbaze (~) | 128~131 | 128.7-130.2 |
| Ọdịdị nke ngwọta | Agba ya adịghị oke agba karịa nke e ji mee ntụaka BY7 | Na-agbaso |
| PH | 6.0~7.5 | 6.86 |
| Ihe ndị e tinyere n'ime mmiri | Nwalee dịka EP10.0 siri dị | Na-agbaso |
| Ihe ndị nwere ike ịgbaze ngwa ngwa | Ihe ngwọta ihe nlele ahụ enweghị agba karịa mmiri mmiri kwekọrọA | Na-agbaso |
| Mfu mgbe a kpọrọ nkụ (%) | 20.5 | 0.03 |
| Ntụ e ji sọlfate mee (%) | 20.1 | 0.0 |
| Ihe fọdụrụ na ọkụ (%) | ≤0.1 | 0.0 |
| Ọla dị arọ (mglg) | ≤20 | -20 |
| Mmechi | EZIERE (Debe iwu ahụ na USP2022 na EP10.0standard) | |
Ojiji
- Mmiri mmiri, njikwa mmanụ, na ibelata isi ojii: Niacinamide nwere ike ibelata mmiri transepidermal nke ọma. Ọ bụ ezie na mmetụta ya mgbe ejiri ya naanị adịghị mma dịka nke hyaluronic acid na glycerin, mmetụta ya mgbe ejiri ya mee ihe bụ 1+1>2; niacinamide nwere ike ime ka gland sebaceous "na-arụsi ọrụ ike" dị jụụ, si otú a na-enweta njikwa mmanụ ma na-ebelata isi ojii na ihe otutu.
- Ike mgbochi mgbachi anya dị mma: Ike mgbochi mgbachi anya nke niacinamide dị n'ike ya ime ka ATP rụọ ọrụ, nye keratinocytes ike, mee ka njikọ collagen dịkwuo mma, o nwekwara ike ime ka ọ dị mma, nke enwere ike iji ya na ihe ndị ọzọ na-egbochi mgbachi anya.
- Mmetụta dị mma nke nchekwa anyanwụ: Mmebi nke ụzarị ultraviolet na-akpata n'ahụ mmadụ abụghị naanị ịgbaze akpụkpọ ahụ, kamakwa igbochi ahụ ji alụso ọrịa ọgụ (Chemicalbook) na ọbụna kansa akpụkpọ ahụ. Ọtụtụ nnyocha n'ụlọ na mba ofesi egosila na niacinamide nwere ike ibelata ihe na-eme ka akpụkpọ ahụ ghara ịmịnye onwe ya mgbe a na-eji ultraviolet radieshon eme ihe nke ọma.
- Ọ dị mma nke ukwuu: Ma e jiri ya tụnyere ihe ndị dị ka vitamin C na ihe ndị sitere na resorcinol, niacinamide dị obere nke ukwuu, ndị nwere ụdị akpụkpọ ahụ dị iche iche nwekwara ike iji ya. Agbanyeghị, a ka kwesịrị ilebara anya na ịnagide akpụkpọ ahụ. Dịka ọmụmaatụ, The Ordinary Whitening Essence nke nwere njupụta niacinamide 10% ka nwere ụfọdụ mgbakasị ahụ. Ya mere, ọ kacha mma ịme ule nnabata akpụkpọ ahụ tupu ejiri ya. Jiri ya naanị mgbe ị kwadoro ndidi, ma n'otu oge ahụ, kpachara anya ka ị ghara iji ya na ngwaahịa nwere acid dị ka salicylic acid na mkpụrụ osisi acid iji gbochie oke iwe na akpụkpọ ahụ.
Ọgwụ a bụ ihe na-emepụta amide nke sitere na vitamin B3 na ihe mgbochi PARP.
Ọgwụ vitamin na-esonye na usoro metabolic n'ime ahụ ma ejiri ya gbochie ma gwọọ pellagra na ọrịa ndị ọzọ na-adịghị na niacin.
Niacinamide nwere ike ịgbaze mmiri karịa niacin, mana ọ na-emepụta ihe mgbagwoju anya ngwa ngwa yana vitamin C na mkpụkọ. Usoro ọgwụgwọ ya bụ 30-80mg/kg. Mgbe ejiri ya na ngwaahịa nlekọta akpụkpọ ahụ, ọ nwere ike igbochi akpụkpọ ahụ siri ike, na-eme ka mkpụrụ ndụ akpụkpọ ahụ dị mma, ma na-akwalite ọcha akpụkpọ ahụ. Mgbe ejiri ya na nlekọta ntutu, ọ nwere ike ịkwalite mgbasa ọbara n'isi, na-eme ka follicles ntutu dị mma, na-akwalite uto ntutu, ma gbochie ntutu isi ịdapụ.
Nkwakọ ngwaahịa na Mbupu
25KG/Drum ma ọ bụ dịka ihe ndị ahịa chọrọ.
Ọ bụ nke ngwongwo nkịtị ma nwee ike ibuga ya site n'oké osimiri na ikuku
Debe ma chekwaa
Ndụ nchekwa: ọnwa 24 site na ụbọchị emepụtara ya na ngwugwu mbụ e meghebeghị emepe echekwara n'ebe dị jụụ na kpọrọ nkụ nke na-anaghị anwụ kpọmkwem, mmiri.
Ụlọ nkwakọba ihe ikuku, Ọkụ dị ala, Nkewapụrụ na ihe ndị na-eme ka oxidants, asịd.
