ʻO Nicotinamide/CAS:98-92-0
Wehewehe Pōkole:
Inoa huahana: Nicotinamide
ʻAno:ZA-N
CAS:98-92-0
MF:C6H6N2O
MW: 122.12
ʻANO:
Ka nui o ka paʻa: 1.40
kiko heheʻe: 182 °C
He aniani keʻokeʻo e like me ke nila a i ʻole ka pauka crystalline, ʻala ʻole a ʻala iki paha, me kahi ʻono ʻawaʻawa iki. ʻO kona nui kūlike he 1.4, a ʻo kona kiko heheʻe he 129-131 ℃. Hiki ke hoʻoheheʻe ʻia ka 1g o kēia huahana i loko o 1mL o ka wai, 1.5mL o ka ethanol, a i ʻole 10mL o ka glycerol, akā ʻaʻole i loko o ka ether. ʻO ka pH o kahi hopena wai 10% he 6.5-7.5. He hygroscopicity nāwaliwali kona. He paʻa iki ia, kū i nā waikawa, alkalis, a me nā mahana kiʻekiʻe. He paʻa ia i ka mālamalama a me ka wela i ka ea maloʻo, akā i ka wā e hoʻomehana ʻia ai i loko o nā hopena alkaline a acidic paha, hana ia i ka waikawa nicotinic. ʻO ka LD50 waha i loko o nā ʻiole he 2.5-3.5g/kg, a ʻaʻole i kuhikuhi pono ʻia ka waiwai ADI (ECC, 1990).
kikoʻī
| NĀ MEA | NĀ KIKOʻĪ | HOʻĀʻO HOPENA |
| helehelena | Pauka aniani keʻokeʻo | Hoʻokō |
| Ka hiki ke hoʻoheheʻe ʻia | Hoʻoheheʻe manuahi ʻia i ka wai a me ka ethanol anhydrous, hoʻoheheʻe iki ʻia i ka methylene chloride | Hoʻokō |
|
Ka ʻike ʻana | A: ʻOmo infrared | Hoʻokō |
| B: Ka omo ʻana o ka ultraviolet. ʻO ka lakio A245/A262 he 0.63-0.67 | 0.66 | |
| C.Kromatogrzphy papa lahilahi | Hoʻokō | |
| Hoʻāʻo (%) | 99.0~101.0 | 100.1 |
| Pae hoʻoheheʻe (□) | 128~131 | 128.7-130.2 |
| ʻAno o ka hopena | ʻAʻole ʻoi aku ka ikaika o ke kala ma mua o ka hopena kuhikuhi BY7 | Hoʻokō |
| PH | 6.0~7.5 | 6.86 |
| Nā mea i hoʻopili ʻia | Hoʻāʻo e like me EP10.0 | Hoʻokō |
| Nā mea hiki ke hoʻoheheʻe koke ʻia | ʻAʻohe kala o ka hopena hāpana ma mua o ka fluidA kūlike | Hoʻokō |
| Pohō ma ka maloʻo ʻana (%) | 20.5 | 0.03 |
| Lehu sulfated (%) | 20.1 | 0.0 |
| Koena ma ke ahi ʻana (%) | ≤0.1 | 0.0 |
| Nā metala kaumaha (mglkg) | ≤20 | -20 |
| HOPENA | KUPONO (Hoʻokō me USP2022 a me EP10.0stʻalani) | |
Hoʻohana
- Hoʻomaʻū, kaohi ʻaila, a me ka hōʻemi ʻana i nā ʻeleʻele: Hiki i ka Niacinamide ke hōʻemi pono i ka nalowale o ka wai transepidermal. ʻOiai ʻaʻole maikaʻi kona hopena i ka wā e hoʻohana wale ʻia ai e like me ka hyaluronic acid a me ka glycerin, ʻo ka hopena i ka wā e hoʻohana pū ʻia ai he 1+1>2; hiki i ka niacinamide ke hōʻoluʻolu i nā kelepa sebaceous "overactive", no laila e hoʻokō ai i ka kaohi ʻaila a me ka hōʻemi ʻana i nā ʻeleʻele a me ka ʻākena.
- ʻO ka hiki ke anti-wrinkle maikaʻi: ʻO ka hiki ke anti-wrinkle o ka niacinamide e waiho ana i kona hiki ke hoʻoulu i ka ATP, hāʻawi i ka ikaika i nā keratinocytes, hoʻonui i ka synthesis collagen, a he hiki ke synergistic maikaʻi, hiki ke hoʻohana pū ʻia me nā mea anti-wrinkle ʻē aʻe.
- Ka hopena maikaʻi o ka pale ʻana i ka lā: ʻO ka pōʻino i hana ʻia e nā kukuna ultraviolet i ke kino o ke kanaka ʻaʻole wale ka ʻili ʻana, akā, ʻo ka hoʻopau ʻana i ka pale ʻana (Chemicalbook) a me ke kanesa ʻili. Ua hōʻike ʻia he nui nā noiʻi ma ka home a ma waho e hiki i ka niacinamide ke hōʻemi pono i ka hanana o ka photoimmunosuppression ʻili i ka wā o ka irradiation ultraviolet.
- ʻOluʻolu maikaʻi: Ke hoʻohālikelike ʻia me nā mea hoʻohui e like me ka huaora C a me nā mea i loaʻa i ka resorcinol, ʻoluʻolu loa ka niacinamide a hiki ke hoʻohana ʻia e ka poʻe me nā ʻano ʻili like ʻole. Eia nō naʻe, pono e uku ʻia ka makaʻala i ka hoʻomanawanui ʻili. No ka laʻana, ʻo The Ordinary Whitening Essence me ka 10% niacinamide concentration he huhū iki nō ia. No laila, ʻoi aku ka maikaʻi o ka hana ʻana i kahi hoʻāʻo hoʻomanawanui ʻili ma mua o ka hoʻohana ʻana. E hoʻohana wale ma hope o ka hōʻoia ʻana i ka hoʻomanawanui, a i ka manawa like, e makaʻala ʻaʻole e hoʻohana pū me nā huahana i loaʻa ka waikawa e like me ka waikawa salicylic a me ka waikawa huaʻai e pale aku i ka huhū nui i ka ʻili.
He amide derivative o ka huaora B3 a me ka mea hoʻopaʻa PARP
Hoʻokomo nā lāʻau huaora i nā kaʻina hana metabolic i loko o ke kino a hoʻohana ʻia e pale a mālama i ka pellagra a me nā maʻi ʻē aʻe o ka nele niacin.
ʻOi aku ka maikaʻi o ka hoʻoheheʻe ʻia ʻana o ka Niacinamide i ka wai ma mua o ka niacin, akā maʻalahi ia e hana i nā hui me ka huaora C a me nā puʻupuʻu. ʻO ka nui o ka lāʻau he 30-80mg/kg. Ke hoʻohana ʻia i nā huahana mālama ʻili, hiki iā ia ke pale i ka ʻili ʻino, mālama i ke olakino o nā ʻili ʻili, a paipai i ka hoʻokeʻokeʻo ʻana o ka ʻili. Ke hoʻohana ʻia i ka mālama lauoho, hiki iā ia ke paipai i ke kahe koko i loko o ke poʻo, mālama i ke olakino o nā follicle lauoho, paipai i ka ulu ʻana o ka lauoho, a pale i ka nalowale o ka lauoho.
ʻŌpala a me ka Hoʻouna ʻana
25KG/Drum a i ʻole e like me nā koi a ka mea kūʻai aku.
No nā waiwai maʻamau a hiki ke hāʻawi ma ke kai a me ka lewa
Mālama a me ka mālama ʻana
Ola papa: 24 mahina mai ka lā i hana ʻia ai i loko o ka pahu i wehe ʻole ʻia mua i mālama ʻia i kahi maloʻo a me kahi anuanu, mai ka lā pololei, ka wai.
Hale kūʻai ea, hoʻomaloʻo wela haʻahaʻa, hoʻokaʻawale ʻia mai nā mea hoʻomake a me nā waikawa.
