I-Milrinone/CAS: 78415-72-2
Incazelo emfushane:
Igama lomkhiqizo: I-Milrinone
I-CAS: 78415-72-2
I-MF: C12H9N3O
I-MW: 211.22
ISAKHIWO:
incazelo
| Into | Imininingwane
|
| Ukubukeka | impuphu emhlophe qhwa |
| iphuzu lokuncibilika | >3000C |
| iphuzu lokubila | 350.9°C |
| ukuminyana | 1.1922 |
| inkomba yokubuyisa | 1.5700 |
| izimo zokugcina | 2-8°C |
| I-coefficient ye-asidi (pKa) | 7.21±0.10 |
Ukusetshenziswa
Imithi emisha ye-cardiotonic engeyona i-glycoside kanye ne-non-catecholamine inemiphumela efanayo ne-amrinone. Inemiphumela emihle ye-inotropic enamandla, ephindwe cishe izikhathi ezingu-20 kuya kwezingu-50 kune-amrinone. Futhi inemiphumela esobala ekukhuliseni imisipha ebushelelezi yemithambo yegazi, inganciphisa umthwalo wenhliziyo, futhi ingathuthukisa kakhulu ukuhlinzekwa kwegazi ezinso nasemisipheni. Kokubili ukuphathwa ngomlomo kanye nangemithambo yegazi kuyasebenza, futhi akukho miphumela emibi kakhulu. Isetshenziselwa ukwehluleka kwenhliziyo okungapheli, ukwehluleka kwenhliziyo okuvalekile kanye nokunye ukwehluleka kwenhliziyo okukhulu.
Imithi ye-cardiotonic inemiphumela yokuthuthukisa ukugoba kwe-myocardial kanye nokukhulisa imithambo yegazi ngokuqondile.
1. Kungase kubonakale ama-ventricular arrhythmias, ama-supraventricular arrhythmias, njll.; iziguli ezimbalwa zingase zizwe izimpawu ezifana nekhanda elibuhlungu, ama-ventricular arrhythmias, ubuthakathaka, ukwehla kwenani lama-platelet, njll.; uma kwenzeka ukudlula ngokweqile, i-hypotension kanye ne-tachycardia kungenzeka; i-bronchospasm kanye nomkhuhlane kuyabonakala ngezikhathi ezithile. 2. Akuvunyelwe ezigulini ezine-acute myocardial infarction. 3. Kufanele isetshenziswe ngokuqapha ezigulini ezine-hypotension, i-tachycardia, ukwehluleka kwezinso, i-atrial fibrillation noma i-flutter (Chemicalbook), izinkinga ze-electrolyte, ama-arrhythmias abangelwa izidakamizwa, izifo zezinso, izifo ezinzima ze-aortic noma ze-pulmonary valve, njll., abesifazane abakhulelwe, kanye nabesifazane abancelisayo. 4. Ukususwa kwengxenye yokuphila kwalomkhiqizo ezigulini ezine-renal insufficiency kwandiswa kakhulu. Ngakho-ke, iziguli ezine-renal insufficiency kufanele zinciphise umthamo futhi zehlise izinga lokufakwa. Asikho isidingo sokulungisa umthamo weziguli esezikhulile.
Ukupakisha Nokuthumela
25KG/Isigubhu noma ngokwezidingo zamakhasimende.
Kungokwempahla evamile futhi kungathunyelwa ngolwandle nangomoya
Gcina futhi ugcine
Isikhathi sokuphila: Izinyanga ezingama-24 kusukela ngosuku lokwenziwa kwento epakishweni lokuqala elingavulwanga, igcinwe endaweni epholile neyomile kude nokukhanya kwelanga okuqondile, amanzi.
Indawo yokugcina izinto enomoya, Ukomisa okuphansi kwezinga lokushisa, Ihlukaniswe nama-oxidants, ama-acid.
