I-Milrinone/CAS: 78415-72-2
Inkcazo emfutshane:
Igama lemveliso: iMilrinone
I-CAS: 78415-72-2
I-MF: C12H9N3O
I-MW: 211.22
ULWAKHIWO:
iinkcukacha
| Into | Inkcazo
|
| Inkangeleko | umgubo omhlophe qhwa |
| Indawo yokunyibilika | >3000C |
| indawo yokubila | 350.9°C |
| uxinano | 1.1922 |
| isalathisi sokuchasana | 1.5700 |
| iimeko zokugcina | 2-8°C |
| I-acidity coefficient (pKa) | 7.21±0.10 |
Ukusetyenziswa
Amayeza amatsha e-cardiotonic angengo-glycoside kunye namayeza angengo-catecholamine anemiphumo efanayo ne-amrinone. Anemiphumo emihle ye-inotropic, ephindwe malunga nama-20 ukuya kuma-50 kune-amrinone. Akwanayo nemiphumo ecacileyo ekwandiseni izihlunu ezithambileyo zemithambo yegazi, anokunciphisa umthwalo wentliziyo, kwaye anokuphucula kakhulu ukuhanjiswa kwegazi kwizintso nakwimisipha. Ukufakwa ngomlomo nangokwemithambo kuyasebenza, kwaye akukho miphumo mibi imbi. Asetyenziselwa ukusilela kwentliziyo okungapheliyo, ukusilela kwentliziyo okuxineneyo kunye nezinye iingxaki zentliziyo ezinzima.
Amayeza e-cardiotonic anefuthe lokuphucula ukuqiniswa kwe-myocardial kunye nokwandisa ngokuthe ngqo imithambo yegazi.
1. Kunokubonwa ii-ventricular arrhythmias, ii-supraventricular arrhythmias, njl.njl.; izigulana ezimbalwa zinokufumana iimpawu ezifana nentloko ebuhlungu, ii-ventricular arrhythmias, ubuthathaka, ukwehla kwenani leeplatelet, njl.njl.; kwimeko yokugqithisa, i-hypotension kunye ne-tachycardia zinokwenzeka; i-bronchospasm kunye nomkhuhlane ngamanye amaxesha zibonwa. 2. Ayivumelekanga kwizigulana ezine-acute myocardial infarction. 3. Kufuneka isetyenziswe ngononophelo kwizigulana ezine-hypotension, i-tachycardia, ukungasebenzi kakuhle kwezintso, i-atrial fibrillation okanye i-flutter (Chemicalbook), iingxaki ze-electrolyte, ii-arrhythmias ezibangelwa ngamayeza, izifo zezintso, izifo ze-aortic okanye ze-pulmonary valve ezinzima, njl.njl., abafazi abakhulelweyo, kunye nabasetyhini abancancisayo. 4. Ukususwa kwesiqingatha sobomi sale mveliso kwizigulana ezine-renal insufficiency kwandiswa kakhulu. Ke ngoko, izigulana ezine-renal insufficiency kufuneka zinciphise idosi kwaye zinciphise izinga lokufakwa. Akukho mfuneko yokulungisa idosi kwizigulana ezindala.
Ukupakishwa kunye nokuthunyelwa
25KG/Idrama okanye ngokweemfuno zomthengi.
Yeyokwempahla eqhelekileyo kwaye inokuhanjiswa ngolwandle nangomoya
Gcina kwaye ugcine
Ixesha lokuphelelwa: Iinyanga ezingama-24 ukususela kumhla wokwenziwa kwayo kwiphakheji yokuqala engavulwanga igcinwe kwindawo epholileyo neyomileyo kude nelanga elithe ngqo, amanzi.
Indawo yokugcina umoya, Ukomisa kubushushu obuphantsi, Yahlulwe kwii-oxidants, ii-asidi.
