Musi wa11 Zvita 2024, kambani inotungamira yebiotechnology yemuno yakazivisa kuti yakanga yabudirira zvikuru mukutsvagisa nekugadzira recombinant human serum albumin (rHSA). Kubudirira uku kunoratidza nhanho yakakosha yekufambira mberi kweChina mumunda we biomedicine uye kunewo simba guru muindasitiri yehutano yepasi rose.
Recombinant human serum albumin imhando ye human serum albumin inogadzirwa kuburikidza ne genetic engineering technology. Serum albumin chimwe chezvinhu zvikuru zveprotein mu plasma yemunhu, zvichiita 50% kusvika 60% yeprotein yese ye plasma. Inoita basa rakakosha mukuchengetedza plasma colloid osmotic pressure uye kutakura zvinhu zvakasiyana-siyana (zvakaita semahormone, mavhitamini, zvicherwa, nemishonga). Pamusoro pezvo, albumin ine mabasa akawanda emuviri, anosanganisira kupa chikafu, kubvisa chepfu mumuviri, uye kudzora mashandiro ekudzivirira muviri.
Kwenguva yakareba, albumin yeropa revanhu yave ichitorwa zvakanyanya kubva muplasma yevanhu. Zvisinei, nzira iyi ine zvipingamupinyi zvakawanda, zvakaita sekushomeka kwezvinhu zvakagadzirwa, njodzi yekusvibiswa nehutachiona, uye kuoma kwemaitiro ekubvisa. Nekuwedzera kuri kuramba kuchiita zvinodiwa pakurapa, kuwanikwa kwe albumin yeropa revanhu yechisikigo hakusi kuzadzisa zvinodiwa pakurapa. Kubuda kwe albumin yeropa revanhu yakasanganiswa kwakapa nzira inoshanda yekugadzirisa dambudziko iri.
Sekureva kwemunhu aitungamira kambani ye biotechnology, vakashandisa tekinoroji yepamusoro yekugadzira majini kuti vaunze gene re serum albumin mumasero chaiwo (akadai seyeast kana masero emhuka dzinoyamwisa) uye vakagadzira recombinant human serum albumin ine kuchena kwakanyanya uye inoshanda zvakanyanya kuburikidza nekukura kwemasero makuru. Iyi tekinoroji haingogadzirisi chete kushanda zvakanaka kwekugadzira asiwo inoderedza zvakanyanya mari yekugadzira uye njodzi yekusvibiswa nehutachiona.
Mushure mekuongororwa kwakasimba kwekiriniki, recombinant human serum albumin yakagadzirwa panguva ino yakaratidza mashandiro emuviri uye kuchengetedzeka kwakafanana nekwe natural serum albumin. Izvi zvinoreva kuti mune ramangwana, recombinant human serum albumin inogona kushandiswa zvakanyanya mukurapa kwekiriniki, senge kurapa ascites kana kuzvimba kunokonzerwa necirrhosis yechiropa, nephrotic syndrome, hypoproteinemia, nezvimwewo, uye kushandiswa pakurasikirwa neacute albumin kunokonzerwa nekutsva, kukuvara, nezvimwewo. Pamusoro pezvo, recombinant human serum albumin inogona zvakare kushandiswa se plasma volume expander mumamiriro ezvinhu ekukurumidza akadai sekuvhiyiwa uye shock.
Nyanzvi dzezveindasitiri dzakataura kuti kubudirira kwekutsvaga nekugadzira recombinant human serum albumin hakungorerutsi kushomeka kwealbumin chete asiwo kunokurudzira budiriro itsva yeindasitiri yezvekurapa. Nekukura kuri kuramba kuchiita tekinoroji iyi uye kudzikiswa kwemitengo, recombinant human serum albumin inotarisirwa kushandiswa zvakanyanya pasi rose mune ramangwana, zvichiunza mabhenefiti kuvarwere vakawanda.
Kambani ye biotechnology yakati icharamba ichiwedzera mari mukutsvaga nekuvandudza, kukurudzira maitiro ekugadzira recombinant human serum albumin, uye kuongorora mashandisirwo ayo mune mamwe mabasa. Panguva imwe chete, vachashanda pamwe chete nemasangano ekurapa emuno neekunze kwenyika pamwe nemasangano ekutsvagisa kuti vawedzere kusimbisa nekuvandudza hurongwa hwekiriniki hwekushandisa recombinant human serum albumin.
Nguva yekutumira: Zvita-11-2024
