I-asidi ye-cholic/CAS: 81-25-4
Inkcazo emfutshane:
Igama lemveliso:I-asidi ye-cholic
Uhlobo:ZA-F
I-CAS: 81-25-4
MF:C24H40O5
I-MW:408.57
ULWAKHIWO:
iinkcukacha
| Into | Iinkcukacha |
| Inkangeleko | eqinileyo |
| Umbala | Mhlophe ukuya kumdaka |
| Ukunyibilika kwamanzi | 0.28 g/L (15 ºC) |
| I-acidity coefficient (pKa) | 4.98 (kwi-20℃) |
| Indawo yokunyibilika | 200-201 °C (elikhanyayo) |
| Uxinano | 1.0310 (uqikelelo oluqikelelweyo) |
| indawo yokutsha | 9℃ |
| imeko yokugcina | 2-8°C |
| ukunyibilika | Inyibilika kwi-methanol, inokunyibilika kwe-0.1g/mL kwaye ibonakala icacile. |
| I-LogP | 2.03-2.615 kwi-20℃ |
Ukusetyenziswa
I-asidi ye-cholic yi-metabolite enxulumene nomninimzi kunye ne-microbiota. Ibonakala njengee-flakes ezingenambala okanye ii-crystalline powders ezimhlophe. Ilawula ukhuseleko lomninimzi kunye nokuba yingozi kwee-microorganisms. Emva kokuba yenziwe ngaphakathi komninimzi, i-asidi ye-cholic ikhutshwa emathunjini, apho ii-microorganisms zinokuyicola ngakumbi ibe ziintlobo ngeentlobo zee-asidi ze-cholic eziphambili nezesibini. Ezi asidi zifunyenwe zidlala indima ekulawuleni amasosha omzimba kunye nemisebenzi yokulwa neentsholongwane.
Isetyenziswa kuphando lwe-biochemical kunye nanjenge-intermediate yezamayeza. I-sodium cholate sisiyobisi esikhuthaza i-bile, esisetyenziselwa ukunyanga izifo ezifana ne-cholecystitis, ukungabikho kwe-bile, kunye nokungagaywa kakuhle kwamathumbu.
I-asidi ye-organic enesakhiwo se-steroid, esinokukhupha amafutha kwaye siphucule impembelelo yawo yokugaya ukutya.
Isicoci se-ionic esingaguquliyo sokukhupha iiproteni ze-membrane
Isicoci esingeyiyo i-ionic sokukhupha iiproteni ze-membrane.
Ukupakishwa kunye nokuthunyelwa
25KG/Idrama okanye ngokweemfuno zomthengi.
Yeyokwempahla eqhelekileyo kwaye inokuhanjiswa ngolwandle nangomoya
Gcina kwaye ugcine
Ixesha lokuphelelwa: Iinyanga ezingama-24 ukususela kumhla wokwenziwa kwayo kwiphakheji yokuqala engavulwanga igcinwe kwindawo epholileyo neyomileyo kude nelanga elithe ngqo, amanzi.
Indawo yokugcina umoya, Ukomisa kubushushu obuphantsi, Yahlulwe kwii-oxidants, ii-asidi.
