Mukurapa zvirwere zvemwoyo, kukundikana kwemoyo kwagara kuri dambudziko rakaoma rinokwezva vanhu vakawanda. Milrinone, nekushanda kwayo kwakanaka, iri kuunza tariro itsva kune vanhu vakawanda vane kukundikana kwemoyo.
Semushonga unoshanda zvikuru we phosphodiesterase inhibitor, milrinone inowedzera zvakanyanya kugadzikana kwemoyo uye inotambanudza mitsipa yeropa kuburikidza nenzira yakasiyana yekushanda. Hunhu uhwu hunoita kuti ikwanise kushanda zvakanaka mukuvandudza mashandiro emwoyo, kukurumidza kuderedza zviratidzo zvakaita sekushaya simba uye kuneta muvarwere vane chirwere chemwoyo, uye kuvandudza zvakanyanya hupenyu hwevarwere.
Kana ichienzaniswa nemishonga yechivanhu yekurapa, milrinone ine mabhenefiti akawanda. Inoshanda nekukurumidza uye inogona kushanda munguva pfupi, zvichiita kuti varwere vanzwe kurerukirwa kwezviratidzo nekukurumidza. Uyezve, milrinone inoshanda kwenguva refu, ichipa varwere vimbiso yekurapwa yakagadzikana. Mukushandiswa kwekiriniki, milrinone yakaratidzwa kuti ine mhedzisiro yakakura pakurapa kutadza kwemoyo kunokonzerwa nezvikonzero zvakasiyana-siyana. Ingave kutadza kwemoyo kunokonzerwa nechirwere chemwoyo, cardiomyopathy, kana chirwere chemwoyo chevalvular, milrinone inogona kuratidza kushanda kwayo kukuru.
Kune vashandi vezvehutano, milrinone iri nyore kushandisa uye chiyero chayo chiri nyore kugadzirisa. Inogona kushandiswa kugadzira zvirongwa zvekurapa zvinoenderana nemamiriro ezvinhu chaiwo evarwere. Kuchengetedzeka kwayo kwakasimbiswawo nemiedzo yakaoma yekiriniki, uye maitiro asina kunaka anogona kudzorwa, zvichipa vanachiremba sarudzo yakavimbika mukurapa kutadza kwemoyo.
Milrinone iri kutungamira nzira itsva mukurapa kutadza kwemoyo uye kuchengetedza hutano hwevarwere. Kusarudza milrinone zvinoreva kusarudza chirongwa chekurapa chemhando yepamusoro, zvichiunza mukana wekudzorera hupenyu hwakanaka kuvarwere. Ngatibatanei ne milrinone kuti tikunde pamwe chete dambudziko rehutano rekushaya moyo uye tipe simba idzva muhupenyu hwevarwere.
Nguva yekutumira: Kubvumbi-08-2025
