Ascorbyl Palmitate/CAS:137-66-6
Description:
Ascorbyl palmitate is a lipophilic derivative of ascorbic acid with antioxidant and antiproliferative activities. It scavenges hydroxyl radicals in cell-free assays. Ascorbyl palmitate (0.01%) reduces the rate of autoxidation of soybean, safflower, sunflower, peanut, and corn oil. It inhibits increases in epidermal ornithine decarboxylase activity and DNA synthesis induced by phorbol 12-myristate 13-acetate (TPA; ) in mice in a concentration-dependent manner when applied topically. Ascorbyl palmitate (0.8 and 4 μmol per 200 μl of acetone, applied topically) reduces the number of tumors per mouse and the percentage of mice with tumors in a mouse skin two-stage model of tumor formation initiated and promoted by 7,12-dimethylbenz[a]anthracene (DMBA) and TPA, respectively. Formulations containing ascorbyl palmitate have been used as antioxidants and preservatives in foods, pharmaceuticals, and cosmetics.
Specification:
|
Item |
Standard |
|
Color |
White or yellowish-white |
|
Odor |
Slightly citrus smell |
|
Appearance |
Powder |
|
Solubility |
Clear |
|
Appearance of Solution |
Clear and not more intensely colored than reference solution BY4 |
|
Assay (%) |
98.0~100.5 |
|
Optical (Specific) Rotation[α] D 25 (°) |
+21~+24 |
|
Melting Range (℃) |
107~117 |
|
Loss on Drying (%) |
NMT 1.0 |
|
Residue on Ignition (%) |
NMT 0.1 |
|
Sulphated Ash (%) |
NMT 0.1 |
|
Residual Solvent (%) |
NMT 0.5 |
|
Arsenic (mg/kg) |
≤0.5 |
|
Cadmium (mg/kg) |
≤0.5 |
|
Lead (mg/kg) |
≤0.5 |
|
Mercury(mg/kg) |
≤0.1 |
|
Total Aerobic Microbial Count (cfu/g) |
< 1000 |
|
Total Yeast and Moulds Count (cfu/g) |
<100 |
Usage
Ascorbyl Palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat soluble form of vitamin C. It is used as an antioxidant food additive. It is also used as a preservative and an anti-oxidant in cosmetic creams and lotions to prevent rancidity. Ascorbyl palmitate facilitates the incorporation of ingredients such as vitamins A, C, and D into cosmetic formulations. It has no known toxicity.
Packaging and Shipping
25KG/Drum or as customer requirements.
Belongs to common goods and can deliver by ocean and air
Keep and storage
Shelf life:24 month from date of manufacture in original unopened packaging stored in a cool dry place out of direct sunlight, water.
Ventilated warehouse, Low temperature drying, Separated from oxidants, acids.









