Thiotaurine: Impinduka mu by’imirire itangaza igihe gishya cy’ubuzima bwo kwirinda indwara

Ubushakashatsi burambuye bwasohotse mu kinyamakuru Nature Reviews Endocrinology bugaragaza ko kuvumbura ibintu bikomeye mu bushakashatsi ku bijyanye n’aside amine birimo guhindura ahazaza h’inyongera mu mirire. Thiotaurine, ikomoka kuri taurine irimo sulfur, yagaragaye nk'ikintu cy’ingenzi gifite inyungu nyinshi ku buzima. Iri terambere rya siyansi ryitezwe gusobanura ingamba zo kurwanya gusaza, indwara ziterwa n’imikorere y’umubiri, n’ububyimbirwe budakira.

Ubwiza bwa Thiotaurine buturuka ku miterere yayo yihariye ikungahaye kuri sulfur, ibyo bikaba byongera ubushobozi bwo kubaho no kwinjira mu turemangingo ugereranije n'ikintu cyayo. Ibyavuye mu bushakashatsi buherutse gukorwa harimo:

Kugabanya stress ya oxidative: Isesengura ryakozwe ku bushakashatsi 28 bwakozwe ku buvuzi ryagaragaje ko Thiotaurine igabanya ibimenyetso bya oxidative ku kigero cya 40-55%, ikaba irusha Vitamine C na glutathione akamaro k’igihe kirekire.

Uburyo bwo kuvura indwara ziterwa n’ubushyuhe: Abashakashatsi bo muri Kaminuza ya Tokyo bavumbuye ko Thiotaurine ibuza NLRP3 gukora ku ndwara ziterwa n’ubushyuhe, ikaba ari inzira ikomeye ifitanye isano n’indwara za rubagimpande n’indwara z’umutima n’imitsi.

Guteza imbere imikorere y’ibinure mu mubiri: Ubushakashatsi bwakozwe mu 2025 muri ETH Zurich bwagaragaje ko Thiotaurine yongera imikorere ya mitochondrial mu mubiri w’amavuta, bigatuma ibinure byiyongeraho 22% mu gihe cy’imyitozo ngororamubiri.

Uburinzi bw'imitsi: Igeragezwa ryakozwe mbere y'isuzuma ryerekanye ko Thiotaurine ibuza amyloid-β kwishyira hamwe, bigatanga uburyo bwo kuvura indwara ya Alzheimer.

“Thiotaurine igaragaza intambwe ikomeye mu guhanga udushya mu mirire,” nk'uko byatangajwe na Dr. Michael Brown, umuyobozi w’ikigo cy’ubushakashatsi ku bageze mu za bukuru cya Salk Institute. “Ubushobozi bwayo bwo guhindura inzira nyinshi z’ibinyabuzima icyarimwe bukemura ikibazo cy’indwara ziterwa n’izabukuru.”

Impuguke mu nganda zigaragaza ko Thiotaurine ishobora kubangamira amasoko mpuzamahanga ya miliyari 50 z'amadolari, harimo imirire ya siporo, kongera ubushobozi bwo gutekereza, no gucunga indwara za metabolic. Igipimo cy'abakiriya kirimo kwihuta bitewe na:

Umutekano: LD50 irenga 5,000mg/kg mu bushakashatsi ku nyamaswa

Intambwe igaragara mu mategeko: Isuzuma ryihuse ryakozwe na FDA na EMA ku bijyanye n'uko ibiryo bihagaze

Ubusabe bw'abaguzi: Gushaka amakuru kuri Google ku "inyungu za thiotaurine" byiyongereyeho 300% ugereranyije n'umwaka ushize

Uko igeragezwa ry’ubuvuzi ryagutse rigashyirwamo abana n’abageze mu zabukuru, Thiotaurine yitezweho kuba igice cy’ibanze cy’amabwiriza agenga imirire myiza. Ibigo bikomeye by’amashuri ubu birimo gukora iperereza ku ruhare rwabyo mu gukira kwa COVID-19 no kwangirika kw’amagufwa afitanye isano n’izabukuru.